Wata ƙungiyar bincike ta haɗin gwiwa daga Makarantar Kiwon Lafiya ta Harvard (HMS) da Babban Asibitin MIT sun ce sun sami nasarar daidaita fitowar na'urar laser microdisk ta amfani da hanyar etching PEC, suna yin sabon tushen nanophotonics da biomedicine "alƙawari."
(Za'a iya daidaita fitarwa na laser microdisk ta hanyar PEC etching)
A cikin filayennanophotonicsda kuma biomedicine, microdiskLaserkuma nanodisk lasers sun zama masu ban sha'awahanyoyin haskeda bincike. A cikin aikace-aikace da yawa kamar on-chip photonic communication, on-chip bioimaging, biochemical sensing, da quantum photon information sarrafa, suna bukatar cimma Laser fitarwa a kayyade tsawon zango da matsananci-kunkuntar band daidaito. Koyaya, ya kasance yana da ƙalubale don kera microdisk da nanodisk lasers na wannan madaidaicin tsayin tsayi akan babban sikeli. Hanyoyin nanofabrication na yanzu suna gabatar da bazuwar diamita na diski, wanda ya sa ya zama da wahala a sami tsayayyen tsayin tsayi a cikin sarrafa taro da samarwa na Laser. Yanzu, ƙungiyar masu bincike daga Makarantar Kiwon Lafiya ta Harvard da Babban Asibitin Wellman na Massachusetts.Magungunan Optoelectronicya ɓullo da wata sabuwar dabarar etching na optochemical (PEC) wacce ke taimakawa daidai daidaita tsayin laser microdisk tare da daidaiton subnanometer. An buga aikin a cikin mujallar Advanced Photonics.
Photochemical etching
A cewar rahotanni, sabuwar hanyar ƙungiyar tana ba da damar kera na'urorin laser na micro-faifai da na'urorin laser nanodisk tare da madaidaicin ƙayyadaddun raƙuman fitar da iska. Makullin wannan ci gaba shine amfani da PEC etching, wanda ke ba da ingantacciyar hanya kuma mai daidaitawa don daidaita tsayin laser microdisc. A cikin sakamakon da ke sama, ƙungiyar ta sami nasarar samun indium Gallium arsenide phosphating microdisks da aka lulluɓe da silica akan tsarin ginshiƙin indium phosphide. Daga nan sai suka daidaita tsayin laser na waɗannan microdisks daidai da ƙayyadaddun ƙima ta hanyar yin etching photochemical a cikin wani diluted bayani na sulfuric acid.
Har ila yau, sun yi bincike kan dabaru da kuzari na takamaiman etchings na photochemical (PEC). A ƙarshe, sun canja wurin tsararrun microdisk mai tsayin tsayin raƙuman raƙuman ruwa zuwa ga madaidaicin polydimethylsiloxane don samar da ɓangarorin Laser keɓe masu zaman kansu tare da tsayin igiyoyin Laser daban-daban. Sakamakon microdisk yana nuna ultra- wideband bandwidth na fitar da Laser, tare daLaserakan ginshiƙin ƙasa da 0.6 nm kuma keɓewar barbashi ƙasa da 1.5 nm.
Buɗe kofa zuwa aikace-aikacen likitanci
Wannan sakamakon yana buɗe kofa ga sabbin nanophotonics da aikace-aikacen ilimin halitta. Misali, microdisk lasers na tsaye kadai zai iya zama barcodes na physico-optical don samfuran halittu masu ban sha'awa, yana ba da damar yin lakabin takamaiman nau'ikan tantanin halitta da kuma niyya na takamaiman ƙwayoyin cuta a cikin bincike na multiplex. A halin yanzu ana yin lakabin takamaiman nau'in tantanin halitta ta hanyar amfani da na'urori na al'ada, irin wannan. a matsayin kwayoyin fluorophores, ɗigon ƙididdiga, da beads masu kyalli, waɗanda ke da faffadan fitar da iska. Don haka, takamaiman nau'ikan tantanin halitta kaɗan ne kawai za'a iya yiwa alama a lokaci guda. Sabanin haka, ɗigon haske mai kunkuntar raɗaɗi na laser microdisk zai iya gano ƙarin nau'ikan tantanin halitta a lokaci guda.
Ƙungiyar ta gwada kuma ta yi nasarar nuna daidaitattun abubuwan da aka gyara microdisk Laser barbashi a matsayin masu alamar halitta, ta amfani da su don yin lakabi na al'ada na nono epithelial sel MCF10A. Tare da fitowar su mai fa'ida mai yawa, waɗannan lasers na iya yuwuwar yin juyin halitta, ta amfani da ingantattun dabarun ilimin halittu da na gani kamar hoto na cytodynamic, cytometry kwarara, da bincike-biyu-omics. Fasahar da ta dogara akan etching PEC alama ce ta babban ci gaba a cikin laser microdisk. Matsakaicin girman hanyar, da madaidaicin subnanometer ɗin sa, yana buɗe sabbin damar don aikace-aikacen laser marasa ƙima a cikin nanophotonics da na'urori masu ilimin halitta, da kuma lambobin barcode don takamaiman adadin tantanin halitta da ƙwayoyin ƙididdiga.
Lokacin aikawa: Janairu-29-2024